Working experience
2015-now
Scientist at the ESRF, working on multicrystal data collection methods, developing cluster analysis software and participating in the operation of structural biology beamlines.
2011-2014
PhD student at the Institut de biologie structural, working on acetylcholinesterase and its complexes with reactivators against organophosphate nerve agents, by means of protein crystallography and molecular dynamics simulation.
2010
Master trainee at the LPSC, working on analytical and numerical modeling of beam-beam interaction in an electron-positron collider.
Publications
Hierarchical clustering for multiple-crystal macromolecular crystallography experiments: the ccCluster program
G Santoni, U Zander, C Mueller-Dieckmann, G Leonard, A Popov
Journal of Applied Crystallography 50 (6), 1844-1851 2017
Design, synthesis and biological evaluation of novel tetrahydroacridine pyridine-aldoxime and-amidoxime hybrids as efficient uncharged reactivators of nerve agent-inhibited acetulcholinesterase
M Kliachyna, G Santoni, V Nussbaum, J Renou, B Sanson, JP Colletier, …
European journal of medicinal chemistry 78, 455-467 2014
Reaction site-driven regioselective synthesis of AChE inhibitors
E Oueis, G Santoni, C Ronco, O Syzgantseva, V Tognetti, L Joubert, …
Organic & biomolecular chemistry 12 (1), 156-161
12 2014
Inhibition pathways of the potent organophosphate CBDP with cholinesterases revealed by X-ray crystallographic snapshots and mass spectrometry
E Carletti, JP Colletier, LM Schopfer, G Santoni, P Masson, O Lockridge, …
Chemical research in toxicology 26 (2), 280-289
17 2013
Bacterial Expression of Human Butyrylcholinesterase as a Tool for Nerve Agent Bioscavengers Development
X Brazzolotto, A Igert, V Guillon, G Santoni, F Nachon
Molecules 22 (11), 1828
2017
A full list of publication is available on my google scholar profile.